Searchable abstracts of presentations at key conferences in endocrinology

ea0056p668 | Neuroendocrinology | ECE2018

Cigarette smoking and neuroreceptors genetic variations: a handshake between genetic and environmental factors leading to nicotine addiction

Zafar Muhammad Mobeen , Ahmad Imtiaz , Raja Muhammad Saqlain , Kiani Shagufta , Ahmed Muhammad Sheeraz , Raza Shakeel , Gulfraz Muhammad , Kaukab Ghazala

Cigarette smoking is the major cause of disease related deaths in the world. Cigarette smoke contains many harmful chemicals, among them nicotine is the most potent one. The root cause of smoking hazards is nicotine addiction or dependence (ND). Environmental as well as genetic factors are reported to influence smoking which leads to nicotine addiction in all age groups especially. Neurexin1 is a cell adhesion protein important for synapse formation and CHRNB4 is chol...